By combining eggs and sperm from a mother and father with a second egg from a donor, eight healthy children have come into the world, report British media.
It is said to be the first time DNA from three different people is used successfully in an IVF procedure to avoid incurable mitochondrial disease.
"After years of uncertainty, this treatment gave us hope - and then it gave us our child", says a mother of one of the newborn children in a statement via a fertility center in Newcastle, according to BBC.
"Thanks to this incredible development and the support we have received, our little family is now complete. The emotional burden of mitochondrial disease has been lifted", says another newly become parent.
The technique has been legal in the United Kingdom for a decade, reports BBC. However, it is only now that it has proven to work in practice.
Around one in 5,000 children are born with hereditary mitochondrial disease, which occurs when the mitochondria - the cells' power plants - do not function as they should. The defect is passed on from mother to child and can lead to severe disabilities and death.
