The shooting took place in a village in the coastal province of Guayas. Seven of the victims, who were between 20 and 40 years old, died on the spot and the eighth person in hospital.
According to local authorities, the perpetrators arrived at the club on motorcycles and in two vehicles. The motive behind the shooting is currently unclear, writes AP.
The area is considered one of the country's most dangerous, at the end of July nine people were killed in a shooting at a bar in the same province.
So far this year, more than 4,600 people have been killed in violent acts in Ecuador this year. According to the authorities, the deadly violence is a product of conflicts between criminal gangs that have links to international drug cartels.