The demonstrations followed the government's announcement to freeze all talks about EU membership for four years. Tens of thousands of Georgians gathered in protests that lasted late into the night in the capital Tbilisi and other cities in the country.
Several demonstrators are reported to have been mistreated by the police, who used tear gas and water cannons and fired rubber bullets at the crowd.
According to the Ministry of the Interior, over 30 employees were injured in connection with the protests, including two female politicians.
The arrested are accused of hooliganism and of not obeying police orders.
Georgia has formal status as a candidate country for EU membership, but the government has increasingly turned towards Moscow in recent years and pushed through several criticized legislative changes similar to Russian models.
Both the opposition and large parts of the Western world have accused the ruling party Georgian Dream of electoral fraud in the disputed election at the end of October.
