Better diagnostics for childhood cancer may become routine

Whole-genome sequencing can soon become a reality throughout Sweden. Three regions have already introduced a diagnostic method that, according to researchers, leads to more tailored treatments for childhood cancer, writes Dagens Nyheter.

» Published: June 28 2024

Better diagnostics for childhood cancer may become routine
Photo: isabell Höjman/TT

Whole-genome sequencing may soon become a reality throughout Sweden. Three regions have already introduced a diagnostic method that, according to researchers, leads to more tailored treatments for childhood cancer, writes Dagens Nyheter.

Since 2021, all cancer-stricken children in Sweden have been part of the research project GMS Childhood Cancer, where they have been offered whole-genome sequencing. A diagnostic method that maps the cancer cells' genetic material in detail to enable treatment with better effect.

So far, the whole-genome sequencing has been funded by the Childhood Cancer Foundation and government funds. But now, researchers want the regions to take over the examination by incorporating it into their routine healthcare.

In the project, you can see that the research during the study becomes clinically useful, says David Gisselsson Nord, national coordinator for the project, to Dagens Nyheter.

Despite the process of getting started being expensive, Region Skåne, Norra Sjukvårdsregionen, and Region Stockholm have already incorporated it into their routine. At the same time, David Gisselsson Nord says it is important that the research continues.

We must not forget that it is a constant fight against cancer cells that quickly adapt to new medicines, he says to DN.

A child becomes ill.

Diagnosis at the hospital and treatment begins.

Samples of cancer cells and healthy cells are taken.

Whole-genome sequencing and analysis of the cancer cells' genes.

Treatment can be adjusted based on a more precise diagnosis.

Increased chance of a more tailored treatment.

Source: Childhood Cancer Foundation.

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By TTThis article has been altered and translated by Sweden Herald

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