The Council is to coordinate and govern security issues, including political commitments, according to a statement from the Syrian President's office.
The decision was announced in the form of a decree via the Telegram platform. It is another step in the attempts to implement a comprehensive political direction for Syria, where different armed groups and factions have strong regional footholds.
The need for enhanced national security has also become acute since many Alawites were massacred in a wave of violence in which both security forces and armed groups participated.
The British-based Syrian Human Rights Observatory has estimated that nearly 1,400 civilians were killed in the attacks.
Interim President al-Sharaa, who leads the rebel group HTS (Hayat Tahrir al-Sham) with previous ties to the terrorist networks al-Qaeda and IS, has said that minority groups and religious communities are to be protected.
Under the ousted leader Bashar al-Assad's brutal regime, there was no official national security council.