Biya has ruled Cameroon since 1982. If he wins the election, he will be 99 years old at the end of the next term. But there are many rumors surrounding his health. The president spends a lot of time in Europe and leaves the country's governance to family members and key figures in the party, and it is speculated that it is because he buys expensive healthcare there.
Nine candidates are challenging Biya, including some former allies.
First-time voter Cheukam Ginette wants change and will not vote for Biya. The country has no proper roads, and it is difficult to access healthcare, she says.
I do not trust the electoral process, we know our country all too well, but I am hopeful, she says to AP.
In 2008, Paul Biya changed the law so that it became possible for a president to be re-elected an unlimited number of times.
Cameroon is plagued by internal conflicts and unrest on the border with Nigeria. 43 percent of the country's population lives in poverty, according to the UN.