It is the first official visit by a Syrian president to Washington since Syria's independence in 1946.
The visit comes days after terror-related sanctions against al-Sharaa were lifted, following a vote in the UN Security Council.
al-Sharaa is expected to sign an agreement that will see Syria join a US-led coalition against the terrorist movement IS. According to a source to the AFP news agency, the leaders are also expected to discuss plans for a US military base near the Syrian capital Damascus.
Ahmed al-Sharaa was the leader of the Islamist rebel group HTS which led the overthrow of former President Bashar al-Assad in December last year.
The movement, which was linked to al-Qaeda, has officially disbanded. The United States lifted its terrorist designation of the group in July of this year.
