The tablets with the narcotic preparation captagon were seized in connection with them coming into Syria from Lebanon, the department states.
This is one of the largest drug seizures in the country since the former dictator Bashar al-Assad's regime was overthrown in December.
The captagon trade is believed to have been one of the Assad regime's main sources of income. The illegal turnover was estimated to be larger than Syria's entire official economy.
Assad-allied Hizbollah in Lebanon has also been accused of trading in captagon, which is a kind of amphetamine. In September, the Lebanese military seized 64 million tablets of the preparation in the country's eastern parts.
