The airport was closed for commercial flights when rebel forces captured Damascus at the beginning of December and deposed al-Assad.
Now, international flights are being resumed, announces the Syrian aviation authority according to the state news agency Sana.
During the hiatus, international aid planes and foreign diplomatic delegations have been able to land in Syria. Domestic flights were also resumed in December.
At the same time, the large airline Qatar Airways has announced that the company is resuming its flights to Damascus after 13 years.
Qatar Airways is owned by the state of Qatar, which has been very critical of the Assad regime. The country broke off diplomatic relations with Syria at the beginning of the civil war in the country.