The suspected shooter is dead. The act took place at the Church of Jesus Christ of Latter-day Saints, better known as the Mormon Church, in Grand Blanc, located a few miles north of Detroit.
In pictures and video clips on social media that are said to have been taken at the scene, a massive cloud of smoke is seen rising towards the sky from the burning building.
US President Donald Trump calls the attack "terrible" in a post on Truth Social and urges to pray for the victims.
"This violence epidemic in our country must end, immediately!", he writes.
The act occurs the day after Russell M Nelson, the Mormon Church's highest leader, passed away at the age of 101.