Israel attacked several locations in central Gaza, including Dayr al-Balah and the refugee camps Maghazi and Nuseirat. Several women and children are reported to be among the dead, according to staff at al-Aqsa hospital.
The total number of people killed in the past 24 hours amounts to 56, according to AP's tally.
On Thursday, an area designated by Israel as a so-called humanitarian zone was hit in the attacks.
In a statement on Friday, Israel's military says it struck dozens of Hamas targets in Gaza during the past day.
Meanwhile, negotiations on a ceasefire are expected to resume on Friday in Qatar. Israeli Prime Minister Benjamin Netanyahu's office announces that he has approved a delegation from the intelligence service and the military to continue the negotiations.