The Dow Jones Industrial Average and the broad S&P 500 traded just above zero, while the Nasdaq's technology-heavy composite closed down 0.2 percent.
Among the winners were vaccine developer Moderna and rental service Airbnb, which climbed 5.3 and 4.7 percent respectively. AI giant Nvidia was down 2.2 percent. Image-sharing platform Pinterest reported a 16.8 percent plunge.
New figures showed US inflation fell slightly in January, contributing to a more upbeat mood in Friday's trading. However, the week was weighed down as a new wave of concerns about an AI bubble hit.
For the week as a whole, the S&P 500 fell 1.4 percent, the Dow Jones Industrial Average fell 1.2 percent and the Nasdaq Composite Index fell 2.1 percent.
