In the speech, Delcy Rodriguez promises resistance to the US's intended temporary rule.
What has been done to Venezuela is barbaric, she says.
We demand the immediate release of President Nicolás Maduro, the only president of Venezuela, and his wife.
In the speech, she also announced, according to Venezuelan media, that she had activated a decree previously approved by Maduro, which means that she has de facto power in the country.
According to Rodriguez, this is to "protect the rights of the people, the institutions of the republic and enable an armed struggle."
We are ready to defend Venezuela, we are ready to defend our natural resources, she says.
US President Donald Trump said earlier on Saturday at a press conference that the United States is in the process of appointing a group of people who will directly or indirectly be part of Venezuela's government after the US arrested Nicolás Maduro and brought him to the United States.
Trump then claimed that his Secretary of State, Marco Rubio, had spoken with Delcy Rodriguez, and that she was "willing to do what we believe is necessary to make Venezuela great again."
