It's a very tough week for our organization, says spokesperson Nathalie Meynet at a press conference on Tuesday.
Personnel costs are to be reduced by 30 percent and the organization expects 3,000-4,000 out of a total of 15,000 jobs to disappear.
UNHCR has previously announced that it expects a "substantial reduction" of personnel due to the withdrawal of American aid.
The President of the USA, Donald Trump, has essentially frozen foreign aid since taking office and made it clear that he aims to completely dismantle the aid agency USAID - the world's largest donor, which has accounted for 42 percent of all global financing of humanitarian aid.
In April, Ocha, the UN's coordinating body for humanitarian aid, announced that it would be getting rid of 20 percent of its personnel for the same reason.