The fire broke out in the hotel's restaurant during the night to Tuesday, according to the country's Interior Minister Ali Yerlikaya.
I don't manage to find any of my students. I hope they are okay, says a ski instructor to the privately owned TV channel NTV.
According to the governor Abdulaziz Aydin, two people died after they jumped from the building in panic.
More than 30 people have been injured, reports the state news agency Anatolia.
It is unclear what caused the fire, which occurred during a school holiday when hotels in the area are generally fully booked. Kartalkaya, located about 30 miles east of Istanbul, is a popular ski resort situated in the Köroglu mountain range.
