Sundsvall-born German Emma Aicher leads second-placed Lara Colturi by 36 hundredths of a second after the first 15 skiers have finished.
Cornelia Öhlund is the best-placed Swede in sixth, 1.17 seconds behind Aicher.
Anna Swenn-Larsson's first run puts her in ninth place, while Sara Hector is twelfth.
American superstar Mikaela Shiffrin, who won the season opener last year, is not competing on Saturday.
The second run starts at 13:00.
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