At the close, the OMXS index had fallen 0.3 percent after rising earlier in the day in the wake of an unexpectedly low inflation figure from the United States.
Among the heavyweights in Stockholm, telecom giant Telia fell the most, down 2.3 percent, followed by construction company Skanska, which lost 1.5 percent.
In the opposite direction were the clothing chain H&M and the mining group Boliden, with gains of 1.8 and 1.7 percent, respectively.
The US stock markets started the day on a high note, and after a couple of hours of trading, the New York stock markets were in the red.
Late on Wednesday, chip manufacturer Micron Technology will release a report that may provide a picture of the state of the AI sector.
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