Luis Suárez, who has previously played for Barcelona and Liverpool, was likely hoping to get a chance to play in the World Cup this summer.
But the veteran was snubbed by Uruguayan national team coach Marcelo Bielsa. When Bielsa named the squad, the 39-year-old was not included.
Suárez has not played for the national team for some time, but earlier in May he opened up about making a comeback to the national team.
Uruguay play in Group H and face Cape Verde, Spain and Saudi Arabia.
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