The Dow Jones Industrial Average and the broad-based S&P 500 index fell 0.6 percent and 0.1 percent, respectively. The tech-heavy Nasdaq Composite Index rose 0.4 percent.
Statistics showed that US inflation, according to the CPI measure, rose to 3.3 percent in March, slightly lower than expected.
Investors are hesitant after a shaky ceasefire between the US and Iran ahead of this weekend's peace negotiations, and are trying to understand what those talks might lead to.
A rapprochement is threatened by Iran's continued closure of the Strait of Hormuz and by Israel's ongoing attacks in Lebanon.
Oil is fluctuating around $95.6 - $96 per barrel.
Despite this, the S&P 500 had its best week since November, up 3.6 percent.
The Dow Jones rose 3 percent and the Nasdaq Composite Index rose 4.7 percent during the week.
