It is the Premier League, La Liga, Serie A and Bundesliga that are jointly calling for reforms within the International Football Association Board (FIFA).
In a joint statement, Infantino is accused of actively promoting ideas that exploit the sport, instead of protecting it from them.
Criticism of Gianni Infantino has grown after his now-scrapped plans to sell shares in the World Cup to private investors.
The increasingly pressured Swiss has put forward proposals for reforms, but that has not silenced demands that FIFA needs new leadership.
The next presidential election will be held in March next year. There is no opponent yet to Infantino, who has been president since 2016. The deadline for running as a candidate in the election expires on November 18.
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