It was the home team, San Jose, who took the lead in the match after a goal by 19-year-old Macklin Celebrini.
But then McDavid stepped into action, scoring his 15th career hat trick and assisting on Edmonton's other two goals in the 5–2 victory.
Edmonton now tops the Pacific Division standings, two points ahead of Vegas. San Jose is fighting for a playoff spot and sits in fifth place.
