For about 40 minutes, the astronauts were out of contact as they were behind the Moon.
"We will always choose Earth, we will always choose each other," said astronaut Christina Koch when contact was reestablished.
On Monday evening, local time in Sweden, the Orion spacecraft surpassed Apollo 13's April 1970 record for the farthest distance from Earth reached by humans - 400,171 kilometers.
Orion has now reached the farthest distance from Earth in its journey - 406,771 kilometers.
Astronaut Jeremy Hansen urges "This generation and the next to make sure this record is not long-lived."
The Artemis expedition is expected to land in the Pacific Ocean on Friday.
