Earlier this week, there were reports that Kylian Mbappé would be back from his injury problems. However, there will be no comeback yet.
It's a heavy blow for the capital club, which is forced to do without its top scorer.
This season, Mbappé has scored 24 goals in league play and the 27-year-old leads La Liga's scoring charts.
It was previously announced that Federico Valverde will miss the match after suffering a head injury during this week's high-profile clash with teammate Aurelien Tchouameni. Tchouameni, however, has been selected for tonight's squad.
Barcelona will win the league if they beat or draw with Real Madrid. The match kicks off at 9:00 PM.
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