Alcaraz was the first out in the tournament's fourth round on Sunday morning, Swedish time. The 21-year-old Spaniard led with two straight sets, 7–5, 6–1, against fifteenth-seeded Briton Jack Draper when the latter was forced to retire at the beginning of the third set due to injury.
The 37-year-old Djokovic won in his turn in three straight sets (6–3, 6–4, 7–6) against Czech Jiri Lehacka.
Thus, a rematch of last year's Olympic Games final (Djokovic's victory) and the last two Wimbledon finals (Alcaraz's double victories) awaits in Tuesday's quarterfinal.
For Alcaraz, who has won the US Open, French Championships, and double Wimbledon titles, the possibility of becoming the youngest player ever to win tennis's four biggest tournaments beckons.
Djokovic, who began his professional career in Alcaraz's birth year 2003, is in turn seeking to extend his title record with Grand Slam number 25 and Australian Open number eleven.
German world number two Alexander Zverev will face twelfth-seeded American Tommy Paul in the quarterfinal after defeating Ugo Humbert (6–1, 2–6, 6–3, 6–2).
Paul had a comfortable journey against Alcaraz's compatriot Alejandro Davidovich Fokina and won in three straight sets – 6–1, 6–1, 6–1.